标题:Tunable thermosensitive behavior of multiple responsive chitin作者:Ding, Fuyuan; Tang, Zheng; Ding, Beibei; Xiong, Yuan; Cai, Jie; Deng,Hongbing; Du, Yumin; Shi, Xiaowen
来源出版物:JOURNAL OF MATERIALS CHEMISTRY B 卷:2 期:20 页:3050-3056 DOI:10.1039/c4tb00067f 出版年:2014
摘要:Chitin can be dissolved and homogeneously functionalized in NaOH/urea aqueous solvent. Previously, we reported that chitin modified with acrylamide (AMC) possesses high water solubility and can undergo a solgel transition responding to pH and cationic ions. In this report, we further explored the thermosensitive behavior of this multiple responsive chitin. We showed that the sol-gel transition temperature of AMC can be facilely adjusted by the degree of substitution (DS), pH, polymer concentration and the presence of anions or cations. Importantly, AMC can form a hydrogel at 37 degrees C and return to solution at 4 degrees C by adjusting experimental parameters. We anticipate this multiple responsive chitin may have potential applications in injectable materials and smart drug delivery.
入藏号:WOS:000335225400010
文献类型:Article
语种:English
扩展关键词:PHASE-TRANSITION; BIOMEDICAL APPLICATIONS; HOFMEISTER SERIES; AQUEOUS-SOLUTION;DRUG-DELIVERY;POLYMERS;MACROMOLECULES;HYDROGEL; GEL; POLY(N-ISOPROPYLACRYLAMIDE)
通讯作者地址:Shi, Xiaowen; Wuhan Univ, Sch Resource & Environm Sci, Environm Biotechnol Key Lab, Wuhan 430079, Peoples R China.
电子邮件地址:shixwwhu@163.com
地址:
[Ding, Fuyuan; Tang, Zheng; Xiong, Yuan; Deng, Hongbing; Du, Yumin; Shi, Xiaowen] Wuhan Univ, Sch Resource & Environm Sci, Environm Biotechnol Key Lab, Wuhan 430079, Peoples R China.
[Ding, Beibei; Cai, Jie] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China.
研究方向:Materials Science
ISSN:2050-750X
版权所有 © bwin·必赢(中国)唯一官方网站
地址:湖北省武汉市珞喻路129号 邮编:430079
电话:027-68778381,68778284,68778296 传真:027-68778893 邮箱:sres@whu.edu.cn