标题: Physiological responses and removal mechanisms of ciprofloxacin in freshwater microalgae

作者: Li, Z (Li, Zhuo); Li, SX (Li, Shuangxi); Wu, QR (Wu, Qirui); Gao, XX (Gao, Xinxin); Zhu, LD (Zhu, Liandong)

来源出版物: JOURNAL OF HAZARDOUS MATERIALS  卷: 466  文献号: 133519  DOI: 10.1016/j.jhazmat.2024.133519  提前访问日期: JAN 2024  

摘要: Antibiotics, such as ciprofloxacin (CIP), are frequently detected in various environmental compartments, posing significant risks to ecosystems and human health. In this study, the physiological responses and elimination mechanisms of CIP in Chlorella sorokiniana and Scenedesmus dimorphus were determined. The exposure CIP had a minimal impact on the growth of microalgae, with maximum inhibit efficiency (IR) of 5.14% and 22.74 for C. sorokiniana and S. dimorphus, respectively. Notably, the photorespiration in S. dimorphus were enhanced. Both microalgae exhibited efficient CIP removal, predominantly through bioaccumulation and biodegradation processes. Intermediates involved in photolysis and biodegradation were analyzed through Liquid Chromatography High Resolution Mass Spectrometer (HPLC-MS/MS), providing insights into degradation pathways of CIP. Upregulation of key enzymes, such as dioxygenase, oxygenase and cytochrome P450, indicated their involvement in the biodegradation of CIP. These findings enhance our understanding of the physiological responses, removal mechanisms, and pathways of CIP in microalgae, facilitating the advancement of microalgae-based wastewater treatment approaches, particularly in antibiotic-contaminated environments.

作者关键词: Ciprofloxacin; Microalgae wastewater treatment; Photorespiration; RNA-seq

地址: [Li, Zhuo; Li, Shuangxi; Wu, Qirui; Gao, Xinxin; Zhu, Liandong] Wuhan Univ, Sch Resources & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm Bi, Hubei Int Scienti f & Technol Cooperat Base Sustai, Wuhan 430079, Peoples R China.

通讯作者地址: Zhu, LD (通讯作者)，Wuhan Univ, Sch Resources & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm Bi, Hubei Int Scienti f & Technol Cooperat Base Sustai, Wuhan 430079, Peoples R China.

电子邮件地址: ldzhu@whu.edu.cn

影响因子：13.6