标题: Catechol-Based Molecular Memory Film for Redox Linked Bioelectronics

作者: Wu, S (Wu, Si); Kim, E (Kim, Eunkyoung); Chen, CY (Chen, Chen-yu); Li, JY (Li, Jinyang); VanArsdale, E (VanArsdale, Eric); Grieco, C (Grieco, Christopher); Kohler, B (Kohler, Bern); Bentley, WE (Bentley, William E.); Shi, XW (Shi, Xiaowen); Payne, GF (Payne, Gregory F.)

来源出版物: ADVANCED ELECTRONIC MATERIALS  文献号: 2000452  DOI: 10.1002/aelm.202000452  提前访问日期: JUL 2020  

摘要: Redox is emerging as an alternative modality for bio-device communication. In contrast to the more familiar ionic electrical modality: (i) redox involves the flow of electrons through oxidation-reduction reactions; (ii) the aqueous medium is an "insulator" to this electron flow since free electrons do not normally exist in water; and (iii) redox states are intrinsically digital (oxidized and reduced). By exploiting these unique features, a catechol-based molecular memory film is reported. This memory is fabricated by electrochemically grafting catechol to a chitosan-agarose polysaccharide network to generate a redox-active but non-conducting matrix. The redox state of the grafted catechol moieties serves as the 2-state memory. It is shown that these redox states: can be repeatedly switched by diffusible mediators (electron shuttles); can be easily read electrically or optically; are stable for at least 2 h in the absence of energy; are sensitive to biologically relevant oxidizing and reducing contexts; and can be switched enzymatically. This catechol-based molecular memory film is a simple circuit element for redox linked bioelectronics.

入藏号: WOS:000549857800001

语言: English

文献类型: Article; Early Access

作者关键词: catechol; molecular memories; polysaccharides; redox linked bioelectronics; spectroelectrochemistry

地址: [Wu, Si; Shi, Xiaowen] Wuhan Univ, Hubei Engn Ctr Nat Polymers Based Med Mat, Sch Resource & Environm Sci,Hubei Int Sci & Techn, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

[Wu, Si; Kim, Eunkyoung; Chen, Chen-yu; Li, Jinyang; VanArsdale, Eric; Bentley, William E.; Payne, Gregory F.] Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA.

[Kim, Eunkyoung; Bentley, William E.; Payne, Gregory F.] Univ Maryland, Robert E Fischell Inst Biomed Devices, College Pk, MD 20742 USA.

[Chen, Chen-yu; Li, Jinyang; VanArsdale, Eric; Bentley, William E.] Univ Maryland, Fischell Dept Bioengn & Res, College Pk, MD 20742 USA.

[Grieco, Christopher; Kohler, Bern] Ohio State Univ, Dept Chem & Biochem, 100 West 18th Ave, Columbus, OH 43210 USA.

通讯作者地址: Shi, XW (corresponding author)，Wuhan Univ, Hubei Engn Ctr Nat Polymers Based Med Mat, Sch Resource & Environm Sci,Hubei Int Sci & Techn, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

Payne, GF (corresponding author)，Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA.

Payne, GF (corresponding author)，Univ Maryland, Robert E Fischell Inst Biomed Devices, College Pk, MD 20742 USA.

电子邮件地址: shixw@whu.edu.cn; gpayne@umd.edu

影响因子：6.593